Transforming Growth Factor-α Mediates Nuclear Factor κB Activation in Strained Arteries
نویسندگان
چکیده
منابع مشابه
Tumor necrosis factor-α induces transcriptional activation of nuclear factor-κB in insulin-producing β-cells.
We previously showed that tumor necrosis factor-α (TNF-α) induces the dysregulation of intracellular calcium [Ca(2+)](i) in β-cells by decreasing the levels of the cytoplasmic Ca(2+) binding protein calbindin-D(28k). The purpose of the present study was to test the hypothesis that TNF-α-induced dysregulation of [Ca(2+)](i) in insulin-producing β-cells causes proteolytic degradation of IκBα and ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2006
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000237388.89261.47